Specifications
Chemical Name: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 (Melanotan II; MT-2)
Molecular Formula: C50H69N15O9
Molecular Weight: ≈ 1024.18 g/mol
Physical Appearance: White to off-white lyophilized powder
Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 (cyclic 2→7)
Container: 3 mL glass vial (10 mg net content)
Purity: ≥99% verified by HPLC & MS (lot COA via QR)
Intended Use: Laboratory research only (RUO). Not for human or animal consumption.
Description
What is Melanotan II?
Melanotan II is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH), a naturally occurring peptide involved in pigmentation signaling within the body. In research settings, it has been studied for its ability to interact with melanocortin receptors, which play a role in melanin production and various neurological signaling pathways.
Due to its stability and receptor affinity, Melanotan II has been widely evaluated in laboratory models focused on melanogenesis, skin pigmentation mechanisms, and melanocortin system activity.
What does Melanotan II do?
In preclinical and laboratory research, Melanotan II is primarily studied for its ability to stimulate melanocortin receptors (MC1R, MC3R, and MC4R). Activation of these receptors initiates signaling cascades that influence melanin synthesis, cellular pigmentation response, and neurochemical pathways associated with appetite and arousal.
One of the most researched outcomes of melanocortin activation is melanogenesis — the process by which melanocytes increase melanin production in response to signaling stimuli. This mechanism has made Melanotan II a compound of interest in studies examining pigmentation biology and UV-response signaling.
Beyond pigmentation, Melanotan II has also been evaluated in experimental models examining:
• Melanocortin receptor signaling pathways
• Neurological and appetite-related signaling
• Cellular UV-response mechanisms
• Hormone-peptide receptor binding dynamics
Its broad receptor activity distinguishes it from more selective melanocortin compounds and makes it a subject of interest in diverse research applications.
Research Context
Melanotan II is studied exclusively in controlled laboratory and educational research environments. Researchers value its predictable receptor affinity and consistent signaling behavior in experimental models involving melanocyte response and neuropeptide interaction.
Because melanocortin receptors influence multiple biological systems, Melanotan II is often evaluated in mechanistic studies rather than applied therapeutic research.
All referenced effects are derived from preclinical and laboratory data only.
Storage & Handling
Storage Before Reconstitution (Lyophilized Peptide)
Unreconstituted (lyophilized) peptides should be stored cold and dry to prevent degradation.
• Short-term storage: 2°C–8°C (36°F–46°F) — standard laboratory refrigeration
• Long-term storage: –20°C (–4°F) or colder
Storage After Reconstitution
Once reconstituted, peptides become more sensitive to temperature, light, and contamination.
• Refrigerated storage: 2°C–8°C (36°F–46°F) for short-term research use
• Frozen storage (if required by protocol): –20°C (–4°F)
Handling best practices:
• Avoid repeated temperature changes.
• Minimize vial access and unnecessary agitation
• Keep protected from light
Return Policy
Due to the nature of our products, all sales are final. We do not accept returns, exchanges, or refunds once an order has been shipped.
Terms & Conditions of Use
By accessing this website or purchasing any product from Pure Source Peptide, you agree to the following Terms & Conditions of Use.
Research Use Only (RUO)
All products sold on this website are designated Research Use Only (RUO). Products are supplied solely for laboratory and educational research purposes and are not intended for human or animal consumption. These products are not approved by the U.S. Food and Drug Administration (FDA) for diagnostic, therapeutic, medical, dietary, or veterinary use and have not undergone clinical evaluation for safety or efficacy.
Eligibility to Purchase
By placing an order, you confirm that:
• You are at least 21 years of age
• You are a qualified professional, institution, or individual conducting legitimate research
• You possess the appropriate knowledge, facilities, and equipment to handle research chemicals safely and responsibly
Prohibited Use
You agree not to use, distribute, resell, or represent any product purchased from this website:
• For human or animal use
• For diagnostic, therapeutic, or medical purposes
• As a dietary supplement, drug, cosmetic, or household product
• In violation of any local, state, federal, or international laws or regulations
Any misuse of products assumes all associated risk and voids any eligibility for claims or support.
